Is the 2021 Mercedes-Benz E-Class reliable?

The 2021 Mercedes-Benz E-Class scores 82/100 (B) on OwnerKeep's reliability index, which places it in the moderate risk category. See the full report for the specific strengths and failure points.

What are the common problems with the 2021 Mercedes-Benz E-Class?

See the Common Issues section above for the top failure areas reported by real owners, with typical mileage ranges where problems start showing up.

How much does it cost to maintain a 2021 Mercedes-Benz E-Class?

Expected maintenance costs depend heavily on age, mileage and how well the vehicle was kept up. Run the full report for a year-by-year cost outlook.

What should I check before buying a 2021 Mercedes-Benz E-Class?

Focus on the top risk areas flagged in this report, review service history, and verify the vehicle is not inside one of the mileage danger zones listed above.

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Reliability AnalysisBased on known issue patterns, repair cost data, and ownership trends · How we score

2021 Mercedes-Benz E-Class Reliability ReportKeepScore 82/100 · top failure points · buy or avoid

82/ 100

KeepScore

MODERATE RISK

Grade: B

A sophisticated luxury sedan offering solid reliability for its segment, but prepare for higher-than-average service costs.

Full system breakdown + what I would do

Quick Facts · 2021 Mercedes-Benz E-Class

Scores 6 points below the strongest nearby year — the 2023 Mercedes-Benz E-Class earns a 88.
The system most likely to surface first: electrical & infotainment (moderate severity).
No active NHTSA safety recalls on record — a clean recall slate for the 2021 model year.

2021 Mercedes-Benz E-Class: Buy or Avoid?

The 2021 Mercedes-Benz E-Class represents a pinnacle of luxury and technology, making it a compelling used purchase for those seeking refinement and prestige. While generally reliable for its segment, owners must be prepared for the inevitable higher maintenance costs and potential for expensive repairs associated with its advanced systems, especially once the factory warranty expires. It's a smart choice for discerning buyers who understand the demands of premium ownership.

Biggest Strengths

Robust powertrain (especially M256 I6)
Exceptional interior quality and comfort
Advanced safety and driver-assist technology

2021 Mercedes-Benz E-Class — Known Trouble Spots

The systems that break first on the 2021 Mercedes-Benz E-Class. Mileage windows, repair costs, and fix-before-you-buy notes are in the full report.

Electrical & Infotainmentmoderate

AIRMATIC Air Suspensionmajor

Engine Ancillaries/Sensorsmoderate

Typical mileage, cost ranges, and the exact what-to-check list are in the full report.

Safety Recalls on the 2021 Mercedes-Benz E-Class

No active NHTSA safety recalls on file for the 2021 Mercedes-Benz E-Class. Always verify with your VIN atnhtsa.gov.

What breaks on the 2021 Mercedes-Benz E-Class?

Full reliability breakdown — engine, transmission, rust, electrical. With repair costs and mileage danger zones.

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Mercedes-Benz E-Class — Year-by-Year Comparison

Compare KeepScores across nearby years of the Mercedes-Benz E-Class. Click any year for its full report.

All Mercedes-Benz E-Class years ranked →Mercedes-Benz E-Class years to avoid →Mercedes-Benz E-Class common problems →

Competing 2021s Worth a Look

Similar class, similar year range — ranked by KeepScore.

2019 ChryslerPacifica

82/100

Relevant Products for Your 2021 Mercedes-Benz E-Class

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Frequently Asked Questions

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